Searchable abstracts of presentations at key conferences in endocrinology

ea0050oc5.3 | Reproduction and Neuroendocrinology | SFEBES2017

Decoding the functional significance of follicle stimulating hormone glycosylation variants

Colley Emily , Wakefield Baylee , Bousfield George , Jonas Kim

FSH and its G protein-coupled receptor (FSHR) are essential for the coordination of reproductive functions. As such, they are a primary target of most assisted reproductive technologies, thus understanding the physiology regulating their function is paramount. Two naturally occurring glycoforms of FSH have been identified-hyperglycosylated FSH (FSH24) and hypoglycosylated FSH (FSH21), based on their ASN glycosylation pattern. The secretion of FSH21 and FSH24 has been shown to ...

ea0050oc5.3 | Reproduction and Neuroendocrinology | SFEBES2017

Decoding the functional significance of follicle stimulating hormone glycosylation variants

Colley Emily , Wakefield Baylee , Bousfield George , Jonas Kim

FSH and its G protein-coupled receptor (FSHR) are essential for the coordination of reproductive functions. As such, they are a primary target of most assisted reproductive technologies, thus understanding the physiology regulating their function is paramount. Two naturally occurring glycoforms of FSH have been identified-hyperglycosylated FSH (FSH24) and hypoglycosylated FSH (FSH21), based on their ASN glycosylation pattern. The secretion of FSH21 and FSH24 has been shown to ...